Young Cal and Derek share a kiss in Season 2, episode 3. Drunk adult Cal comes back and rocks out to Sinead O'Connor in episode 4 before being kicked out.

Ulysses S. Grant High School

High School

Source: Filmap

Moonlight Rollerway

Roller Rink

Rue, Jules and Lexi go roller skating, Lexi tells Jules that Rue is doing good because of her.

Odd Ball Cabaret

Strip Club

Season Two opening. "Fezco's grandma was a motherfuckin' G"

Favorite Liquor

Convenience Store

Elliot and Jules steal beer in Season 2, episode 4.

Travel Inn

Motel used throughout the series, where Cal meets his online dating app hook ups and Nate and Maddy meet on Friday nights.

Source: Filmap

Astro Burgers

Source: Filmap

Pann's Restaurant

Restaurant

Ali takes Rue for pancakes.

Los Angeles Union Station

Train Station

In the season one finale, Jules and Rue decide to run away, but Rue gets cold feet at the train station.

Source: spidermaninlove — Tumblr

Del Amo Fashion Center

Mall

Local mall used multiple times in the show, Nate stalks Tyler, Kat goes on a shopping spree with one of the twins, Kat meets a man, etc.

16104 Clear Oak Dr

Theo's House

Maddy is found babysitting and enjoying the luxuries in this mountain top home through out season 2.

Source: reddit

Knox Presbyterian Church

Church

Rue finds herself in this church for NA and hallucinations throughout the series.

Source: Atlas of Wonders