The Westin Bayshore Hotel as National City City Hall
The team searches for Pestilence after several people in city hall get sick from a mysterious illness.
“Of Two Minds” Filming Locations
As people start getting sick from Pestilence, Kara tries to reign in Irma from being too aggressive while Lena continues her examination of Sam.
Supergirl episode “Of Two Minds” was filmed in Vancouver & Burnaby in Canada.
Ritchie Bros. Auctioneers as Silvermine Health Insurance
The team tracks Pestilence to a health insurance company and learn that she has no interest in stopping her rampage.