The central dirt-covered alley complete with fire escapes and tall industrial facades makes this building a popular filming location.
Finch and Reese break into a warehouse to steal some advanced computers to augment the Machine's PS3 cluster in episode 5x02 “SNAFU”.
Finch works on the Machine and ends up installing the memory erasing program in episode 5x01 “B.S.O.D.”. Finch teaches morality to the Machine in episode 5x02 “SNAFU”.
Simpson shows Jessica the defunct CDC lab where they can take Kilgrave but when they return there later they are attacked by his bodyguards who manage to rescue Kilgrave in episode 1x05 “AKA The Sandwich Saved Me”. Jessica calls a department head at the University of Manchester and learns the names of Kilgrave’s parents in episode 1x09 “AKA Sin Bin”. Kilgrave escapes the building and takes control of Hogarth in episode 1x10 “AKA 1,000 Cuts”.