A group of researchers in the arctic find a frozen wolf body and something goes terribly wrong when they go to dissect it leading to the D.E.O.'s investigation.
Alex comes out to Kara while walking along the waterfront.
Dr. Jones heads back to his lab after being rescued by the DEO and kills his boss who wants to fire him.
Kara responds to reports on an alien attack only to find Mon-El roughing up another alien to collect a debt.
Dr. Jones tries to kill Rand O'Reilly who is saved by Kara & Hank who have to be saved in turn by the DEO.
Mon-El and Guardian stop the mutated Dr. Jones from killing Rand O'Reilly and other bystanders until Supergirl can arrive to stop him once and for all.