After Jess finds her boyfriend cheating, she moves into a loft with three men. Comedy ensues. Main exterior of the loft is downtown, while some scenes imply they live in Westlake District.
From episode 5x08 "The Decision".
Jess and Robby take shelter in a cave during their ill-fated hike in episode 6x14 "The Hike".
Nick drives to the desert instead of moving in with Caroline in the season finale "See Ya."
Nick is a bartender at The Prince.
Some exteriors scenes and most establishing shots use this building as the location of Jess and the gang's loft.
In episode "Kryptonite" Nick, Schmidt, and Winston eat at John O'Groats.
Exterior of Caroline's apartment that Nick was planning on moving in to. The apartment is in the same building as The Prince, the bar Nick works at.
Jess meets Owen (Ryan Kwanten) while looking for a one night stand in season one's episode "Valentine's Day."