The David N. Dinkins Municipal Building is a 40-story government tower opened in 1914 and designed by William M. Kendall. The building was designed in a mishmash of architectural styles, is topped by a golden statue known as Civic Fame, houses over 2000 employees, and is the first building in Manhattan to incorporate a subway station into its construction.
Root and Shaw leave the building after thwarting a murder attempt on Simon Lee in episode 4x05 “Prophets”.
Reese investigates an office across from the courthouse where the fixer was doing his research in episode 4x14 “Guilty”.
Source: NYC Permits List
Bullock & Gordon interview a police officer by a hot dog stand in episode 4x06 “A Dark Knight: Hog Day Afternoon”.
Source: IMDb
The Ghostbusters head out with the police and army to deal with the supernatural threat.
thats not a knife, this is a knife... scene, subway station exit