A large historic hotel in downtown Toronto which opened in 1929 as part of the Canadian Pacific Railway's network of grand hotels across the country. The hotel current sports 1365 rooms, a number of meeting rooms, a bar, and a small shopping area in the basement.
The handmaids attend a fancy dinner so they can be shown off to the Mexican ambassador in episode 1x06 "A Woman's Place".
Offred is escorted into an illicit sex club by Commander Waterford where she spots Moira still among the living in episode 1x08 "Jezebels". Nick escorts Offred and the commander to the club before retiring to the kitchen in an attempt to gather information for the Eyes in episode 1x09 "The Bridge".
Source: Toronto.com (archived)
The U.N. and M.C.R. delegations meet to discuss the events on Ganymede and Bobbie is brought in to testify on what she saw in episode 2x09 "The Weeping Somnambulist". The two delegations return to the negotiating table to settle their deal and Chrisjen asks about Bobbie in episode 2x10 "Cascade".
Sarah and Siobhan go to a hotel bar to steal the ID from Dr. Elizabeth Perkins in episode 5x04 "Let the Children and Childbearers Toil".
Delle Seyah greets Dutch upon her arrival and briefs her on the evening in episode 1x10 "Escape Velocity".
Dutch accompanies Delle Seyah Kendry to an important event in episode 1x10 "Escape Velocity".
Liam jumps into the elevator with Tanz to tell him about the meteor heading for the planet in pilot episode.
Nikita stops Division from assassinating General Safwani in his hotel room in pilot episode.
Nikita and Michael gather information from Timur Ahmedov in order to locate Kasim Tariq in episode 1x09 "One Way".
Bo arrives in the afterlife to rescue Kenzi in episode 5x01 "Like Hell: Part 1".
The power to Dr. Ron's office building shuts down in episode 1x11 "Cocktail Bunny".
Source: The Wonderfalls Tour
Source: IMDb